GPX4 and acute kidney injury: A study reported by Yashpal S. Kanwar et al. (Deng et al., 2019) indicated that Fer-1 treatment improves tubular damage in cisplatin-induced AKI, and alterations in GPX4 expression, NADPH, and GSH levels were observed in cisplatin-treated HK-2 cells, while regulated by Myo-inositol oxygenase.