Tian et al. showed that Chinese herbal medicine Baoyuan Jiedu decoction could inhibit the lung PMN formation and the recruitment of MDSCs in the lungs by suppressing the TGF-β/CCL9 signaling pathway, which promotes the directional movement of tumor cells and completes the lung-targeted metastasis 120. The gene discussed is TGFB1; the disease is neoplasm.