GSR and multiple sclerosis: After melatonin injection the decrease in the content of oxidative stress biomarkers (including MDA) as well as an increase in the activity of antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase) were observed in the tissues of young animals with experimental models of multiple sclerosis (Abo Taleb and Alghamdi, 2020; Murioz-Jurado et al., 2022).