The OXT/OXTR signaling is implicated in a variety of normal behaviors, including social interaction, anxiety-related behavior, depression, maternal behavior, aggression, mating, attachment, and sexual behavior (Ferguson et al., 2001; Yoshida et al., 2009; Neumann and Slattery, 2016; Jones et al., 2017). This evidence concerns the gene OXTR and depressive symptom measurement.