Of the 48 cases with MOG-AD, 24 had acute disseminated encephalomyelitis, 8 had autoimmune encephalitis overlap syndrome, 5 had optic neuritis, 4 had neuromyelitis optica spectrum disorder, and the resting cases had cortical encephalitis, aseptic meningitis, cranial neuritis, or demyelinating pseudotumor (Figure 2C). This evidence concerns the gene MOG and optic neuritis.