Similarly, enriched KEGG analysis provided further support for a strong association between the HDM sensitization and pathways related to inflammation and immunity, including categories such as: cytokine-cytokine receptor interaction, chemokine signalling, IL-17 signalling pathway, toll-like receptor signalling, asthma, c-type lectin receptor pathway and ECM-receptor interaction (Figure 7C). Here, CLEC4D is linked to asthma.