Furthermore, Toll-like receptor 7 and 8 (TLR7/8) mediates the antiviral immune response by recognizing mainly viral RNA, and the increased response of the CCL13 gene to TLR7/8 agonists in the nasal mucosa of asthma patients may reflect the role of the virus in asthma progression (30). The gene discussed is CCL13; the disease is asthma.