CCL13 and AIDS: In a multicenter AIDS cohort study (MACS) conducted from 1984 to 2009, CCL13 was found to be higher in the group of SUP (exposed to HARRT with HIV RNA suppressed to less than 50 copies/ml plasma) compared to the HAART-naive (NAI) group, on the timeline, CCL13 increased significantly in the first year of viral suppression, followed by a uniformly flat trajectory, HIV suppression appeared to increase the levels of the M2-associated chemokines (117).