In addition, increased tumor infiltration of mouse and chicken macrophages in BL tumors, as revealed by IHC detection of the mouse antigen F4/80 and qPCR quantification of the chicken antigen MRCL1 (22), was accompanied by a loss of histone H3-pSer10 nuclear staining, suggestive of a consistent reduction in tumor mitotic index in animals subjected to triplet therapy, when compared to TG-1801 and U2 treatment arms (Figures 2E, F). The gene discussed is CLEC18A; the disease is neoplasm.