TLR4 and infection: In addition, the flow cytometry data showed that the surface expression of TLR4 was reduced upon infection in a significant manner [from 45.33 ± 1.805% to 23.03 ± 2.266%] and it was further decreased nonsignificantly [18.2 ± 0.76%] in presence of TAK-242 treatment (Figure 1C).