Furthermore, tumor immune cell infiltration analysis showed that ATP7A, ATP13A2, and SNCA, which were unfavorable for the OS of patients with HCC, were positively correlated with multiple types of immune cell infiltration, whereas COX17, F5, and ALB, which were favorable for the OS of patients with HCC, were negatively correlated with immune cell infiltration in HCC. Here, F5 is linked to hepatocellular carcinoma.