The level of sPD‐L1 in patients with tumor diameter greater than or equal to 5 cm (median 306.325 pg/mL, range 117.591–539.008 pg/mL) was noticeably higher than that in patients with tumor diameter less than 5 cm (median 98.233 pg/mL, range 38.124–221.432 pg/mL, p = 0.000; Figure1B). Here, SPDL1 is linked to neoplasm.