Association of Löfgren’s syndrome and other milder disease forms with the combination of the following six variants, HLA-A*01:01∼HLA-B*08:01∼HLA-C*07:01∼HLA-DRB1*03:01∼HLA-DQA1*05:01∼ HLA-DQB1*02:01, may be, therefore, considered in the context of the personalized approach to sarcoidosis patients. This evidence concerns the gene HLA-DRB1 and Löfgren’s syndrome.