We analyzed 6 HLA loci (HLA-A,-B,-C,-DRB1,-DQA1, and -DQB1) in 301 unrelated patients with sarcoidosis diagnosed and followed according to the ATS, ERS, and WASOG statement on sarcoidosis (12) at the Department of Pneumology and Phtiseology, University Hospital and Faculty of Medicine, Brno, Czechia and 309 unrelated Czech healthy control subjects, blood donors from the same geographical region of Czechia. Here, HLA-DRB1 is linked to sarcoidosis.