We can also speculate about the effect of HLA-DRB1*03:01 homozygosity on better prognosis as four of five homozygotes among our Czech sarcoidosis patients had a remitting disease, a similar relationship was previously observed in HLA-DRB1*03:01 homozygous patients with remission of multiple sclerosis (29). Here, HLA-DRB1 is linked to multiple sclerosis.