HLA-DQB1*06:02 and HLA-DQB1*06:04 can be considered as susceptibility (risk) factors for sarcoidosis; the frequency of the HLA-DQB1*06:02 in the patients was increased 1.75 times compared with the control subjects, and the HLA-DQB1*06:04 frequency increased four times in the patients. The gene discussed is HLA-DQB1; the disease is sarcoidosis.