HLA-DRB1 and Leigh syndrome: Regarding Löfgren’s syndrome, we report six variants (HLA-A*01:01∼HLA-B*08:01∼HLA-C*07:01∼HLA-DRB1*03:01 ∼HLA-DQA1*05:01∼HLA-DQB1*02:01), forming 8.1 haplotype, to be associated with LS.