Modest increase of EC risk has been suggested in BRCA1 and BRCA2 PV carriers (most notably the serous-like EC subtype), and other hereditary breast and ovarian cancer genes (HBOC; ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, NF1, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53) (17). This evidence concerns the gene BRCA2 and ovarian carcinoma.