According to a number of studies, CX3CL1 plays a critical role in fostering robust anti-tumor activity by recruiting NK cells and T cells into the tumor microenvironment (Xin et al., 2005; Zeng et al., 2005; Nukiwa et al., 2006; Siddiqui et al., 2016). This evidence concerns the gene CX3CL1 and neoplasm.