In addition, in our analysis, eight major immune cell types (CD3+ T-cells, CD8+ T-cells, cytotoxic lymphocytes, NK cells, B lymphocytes, monocytic lineage cells, myeloid dendritic cells and neutrophils) mostly showed low infiltration, and M1/M2 macrophage analysis suggested downregulation of overall inflammation in ACC tissue. The gene discussed is CD8A; the disease is adrenal cortex carcinoma.