In patients with advanced ovarian cancer responding to platinum-based chemotherapy, regardless of their HRR biomarker state, niraparib as a first-line maintenance therapy prolonged the progression-free survival (PFS), prompting the U.S. Food and Drug Administration (FDA) to approve the first PARP inhibitor therapy in April 2020 for the population without BRCA mutation (17). This evidence concerns the gene PARP1 and ovarian carcinoma.