CCG-1423 is a new small molecule inhibitor of the MRTF-A mechanism that can block the transcription of MRTF-A by functionally inhibiting its nuclear localization, and it has been found in experiments that CCG-1423 has a good effect in the treatment of HF and not only blocks the expression of MRTF-A and α-SMA protein but also reduces the degree of HF and collagen content (Hayashi et al., 2014; Zheng et al., 2017). Here, ACTA1 is linked to hydrops fetalis.