LRP1 and epilepsy: Our previous research has found that knockdown/knockout of genes involved in epilepsy or neural disorder, such as UNC13B, LRP1, and YWHAZ, leads to various brain abnormalities, including neuron blurring in mushroom body (Wang et al., 2021), partial destruction in the central complex (Zhang et al., 2022), and gamma lobe mutilation in the mushroom body (Wan et al., 2022).