Expression of KDM5B is increased in several cancer types (Dai et al., 2014; Wang et al., 2015; Bamodu et al., 2016), including PCa (Xiang et al., 2007), with elevated expression implicated in multiple pro-oncogenic mechanisms in many cancer types (Hayami et al., 2010; Krishnakumar and Kraus, 2010; Dai et al., 2014; Shen et al., 2015; Zhao and Liu, 2015; Wang et al., 2016a; Bamodu et al., 2016; Wang et al., 2016b). This evidence concerns the gene KDM5B and cancer.