Meanwhile, p-PFKFB3 can interact with GLUT2 and enhance the expression of GLUT2 (Wang et al., 2020).Among the clinical methods for tumor diagnosis, 2-[18F] fluoro-2-deoxy-D-glucose PET-CT is used as a relatively common means to assess tumors with standardized uptake values (SUVMAX). This evidence concerns the gene SLC2A2 and neoplasm.