TNPO1 and esophageal cancer: CircBCAR3 was found to interact with miR-27a-3p to upregulate transportin 1 (TNPO1) expression, promote esophageal cancer cell proliferation, migration, invasion and ferroptosis, and play an oncogenic role in esophageal cancer by promoting esophageal tumorigenesis and metastasis in mice (Xi et al., 2022).