A logistic regression was performed on poor physical function using GDF-15 tertiles, TNF tertiles, IL-6 tertiles, diabetes, age, years of education, BMI, gender, RAPA, and total MNA-SF, and the B-estimates were used as the weighted scores to develop the prediction model (Table 3), with an AUC of 0.719, 95% CI (0.612–0.826), p = 0.001 (Figure 2). The gene discussed is GDF15; the disease is diabetes mellitus.