Researchers verified that YTHDF2 is involved in the regulation of DEGS2 by mediating the degradation of m6A-modified DEGS2 mRNA, resulting in the inhibition of CRC proliferation and migration (79) It appears that YTHDF2 may act as a double-edged sword in CRC tumorigenesis. The gene discussed is YTHDF2; the disease is colorectal carcinoma.