NFKB1 and neoplasm: The regulation of complex- II by UXT-V1 and the regulation of nuclear events in NF-κB signaling pathway by UXT-V2 clarified the differences between the two isoforms of UXT, enriched the mechanism of action of UXT, provided direct evidence of UXT and cell death, and also hinted at the possibility of UXT participating in the regulation of tumor, inflammation and immunity through the NF-κB signaling pathway.