DNMT3B and breast cancer: UXT-V2 is up-regulated in breast cancer tissues and cell lines, and down-regulates maternal expression 3 (MEG3) by binding to DNMT3B, thereby inhibiting the P53 signaling pathway (22).UXT-V2 also inhibits apoptosis and promotes the proliferation, migration, and invasion of breast cancer cells through its negative regulation of the P53 signaling pathway (22).