Similar to previous findings in patients with AD and (Yang et al., 2011; Peltsch et al., 2014; Chehrehnegar et al., 2019) mild cognitive decline (Peltsch et al., 2014; Laurens et al., 2019; Chehrehnegar et al., 2022) and young apolipoprotein E (APOE) 4 carriers (Niechwiej-Szwedo et al., 2018), we found that individuals with a family history of AD showed a relatively lower velocity. This evidence concerns the gene APOE and Alzheimer disease.