However, there is no direct connection between p53 and Olfm4. After searching for potential Olfm4-interacting proteins and p53-interacting proteins in the STRING database, we found that Mmp9, an ECM enzyme known to be associated with IBD 27, 28, might be a key factor linking Olfm4 with p53. This evidence concerns the gene MMP9 and inflammatory bowel disease.