The expression of these genes correlated with a higher risk of death in patients with NPC.Higher expression of ADCY3 (P = 0.005), ADCY9 (P =0.008), CYP2J2 (P = 0.001), DNMT1 (P <0.001), EPHX1 (P <0.001), MBOAT7 (P <0.001), POLD1 (P = 0.001) and UAP1 (P < 0.001) was associated with worse prognosis in patients with NPC (Fig. S6D). The gene discussed is DNMT1; the disease is nasopharyngeal carcinoma.