ACKR2 and Cryptozoospermia: Besides, two crosstalk networks between SPGs and adjacent microenvironments including “SPGs-FGFR1/3-FGF2-pachytene/diplotene SPCs” and “SPGs-ACKR2-CCL2/3/4/5/3L1/14-EC/immune cells/perivascular cells” were detected in cryptozoospermia rather than normal patients 66.