Besides, scRNA-seq data also revealed perturbed somatic cells in cryptozoospermia, including an obvious increase of PTMs (including fibrotic PTMs) and macrophages, a deep transcriptional change of PTMs, an elevated ratio of MUSTN1 postitive (a pan-musculoskeletal cell marker 117) blood vessels and the gathering of CD3 T cells around blood vessels 66. This evidence concerns the gene MUSTN1 and Cryptozoospermia.