However, flavonoids can inhibit tumor cells through classical signaling pathways such as NF-ΚB, AKT, and AMPK, and it has been demonstrated that luteolin can achieve in vivo and in vivo anti-tumor activity by affecting levels of inflammatory factors, with no apparent toxicity to normal cells and low side effects, further validating its clinical effect 97. The gene discussed is AKT1; the disease is neoplasm.