FAM72A and malignant colon neoplasm: FAM72A, also known as Ugene, is located on chromosome 1q32.1, its encoded protein includes 149 amino acids, its expression is increased in colon cancer, breast cancer, lung cancer, uterine and ovarian tumors, and it functions by binding to DNA-glycosylase 2 (UNG2) of the base excision repair (BER) pathway 13.