TF and Venous thrombosis: Previous studies have shown the NLRP3 inflammasome to be activated in platelets during thrombosis resulting in the secretion of both IL‐1β and tissue factor (TF).[30] IL‐1β along with other mediators are known to promote platelet activation and aggregation, while TF helps to initiate the coagulation cascade by increasing platelet production of fibrinogen, the precursor to fibrin.[31] Our study is in agreement with previous research suggesting a link between NLRP3 inhibition and reduced arterial thrombosis.