Analysis of LUSC data available from The Cancer Genome Atlas (TCGA) showed that over 30% of tumors have an amplification of TP63, which is more frequent compared to other cancers profiled in TCGA (Fig. 1A) and is among the most frequently amplified transcription factors in LUSC (Fig. 1B and Supplementary Table S4). This evidence concerns the gene TP63 and cancer.