TARDBP and frontotemporal dementia: We also measured the ratio between phosphorylated and total TDP-43, which may serve as an index to detect possible formation of aggregates in which p-TDP-43 is abundant, and we found higher values in FTD mice compared to wildtype animals in the mPFC, but this did not happen in the hippocampus (data in Table 1 and blots in Additional file 1: Fig. S1).