Thus, we found a complete normalization by FAAH inhibition in the number of cells positive for the astrocyte marker S100β (F(2,22) = 8.676, p < 0.005; Fig. 16A,B), as well as in the immunoreactivity for the microglial marker Iba-1 (F(2,23) = 9.67, p < 0.001; Fig. 16C,D), which were significantly elevated in FTD mice, as shown before and again in this experiment. Here, FAAH is linked to frontotemporal dementia.