MAPT and frontotemporal dementia: This allows a classification of FTD based on the main component of these cytoplasmic inclusions: (i) FTLD-Tau (40–45% of genetic cases); (ii) FTLD-TDP-43 (40–45%); (iii) FTLD-FUS (5–10%); and (iv) FTLD-UPS (1%) [49, 58, 68].