TARDBP and frontotemporal dementia: Such potential has not been investigated in TDP-43-dependent FTD yet, so that this has been the major objective of the present study, which has been conducted with a murine conditional TDP-43-dependent model of FTD that overexpress this protein exclusively in the forebrain (cortical and subcortical (e.g. hippocampus, striatum) areas) under the control of α-CaMKII promoter [75].