These neuronal losses were also associated in the mPFC of FTD mice at both PND90 and PND365 with elevated levels of S100β, a marker of astrocytes particularly recommended for this structure [88] (genotype: F(1,30) = 49.92, p < 0.005; Fig. 6A,B), and Iba-1, a marker of microglial cells (genotype: F(1,30) = 36.88, p < 0.0005; Fig. 6C,D). Here, AIF1 is linked to frontotemporal dementia.