Our data reflected trends towards an increase in anandamide concentrations of FTD mice, in particular in the mPFC (p = 0.097; Fig. 12G), accompanied by similar responses in two related lipids that are also substrates of FAAH: PEA (p = 0.063 in the mPFC; p = 0.083 in the hippocampus; Fig. 12I) and OEA (p < 0.05 in the mPFC; Fig. 12J), which support such alterations as part of an endogenous protective response. This evidence concerns the gene FAAH and frontotemporal dementia.