The same effect was found, using NeuN immunostaining, in the hippocampal CA1 subfield although to a much lower intensity (F(2,21) = 4.672, p < 0.05; Fig. 15C,D), and was not visible in the dentate gyrus (Fig. 15C,E) in this cohort, in which NeuN immunostaining was poorly affected in FTD mice treated with vehicle (F(2,21) = 1.084, ns), as also found in the first experiment where only a trend towards to be reduced was evident. The gene discussed is RBFOX3; the disease is frontotemporal dementia.