Circ_0002984 forms from the Rho GTPase Activating Protein 32 (ARHGAP32) gene through back-splicing and has a high expression in the peripheral blood mononuclear cells from RA patients, as analyzed through the GSE189338 dataset in the preliminary experiment; however, no study has been performed to analyze circ_0002984 function in RA development. Here, ARHGAP32 is linked to rheumatoid arthritis.