To further validate the value of three of the PRGs in the prognostic model (BAK1, GSDME, and NLRP6) for the development of the diagnostic as well as prognostic signatures, we used HCC cohorts from the GEO database (GSE62232, GSE102079, and GSE112790) and ICGC database to assess the expressions of the three PRGs. Here, GSDME is linked to hepatocellular carcinoma.