Choroszczak et al. [86] investigated changes in VEGF and BFGF serum concentrations in 51 IH patients during propranolol treatment and discovered that serum concentrations of both factors were significantly reduced, possibly due to their inhibitory effects on angiogenesis, induction of endothelial cell apoptosis, and vasoconstriction. Here, VEGFA is linked to isolated hemihyperplasia.