CTNNB1 and central nervous system cancer: When OS and PFS were additionally calculated for the CSNK1A1 and CTNNB1 tertile groups in patients with grade II or III glioma and GBM, the first CTNNB1 tertile group showed a significantly higher PFS rate among patients with grade II or III glioma, while the rest were not statistically significantly different (Fig. 4E-H).