Recently, a phase I/II clinical trial (NCT05114837) has been evaluating the safety, tolerability, and potential anti-tumor efficacy of allogeneic anti-CD19 CAR-Treg in adult patients with relapsed/refractory (R/R) acute lymphocytic leukemia (ALL) [82] (Table 2). The gene discussed is CD19; the disease is acute lymphoblastic leukemia.