GPT and Hepatic fibrosis: In calculating the accuracy of values equal to or greater than twice the upper limit of normal for AST and ALT enzymes as predictors of significant liver fibrosis, a sensitivity of 80% (CI95% 28.4–99.5) and a specificity of 95% (CI95% 75.1–99.9) were observed, which suggests that the longitudinal evaluation of these tests may contribute to the screening of progressive liver fibrosis in these patients during follow-up.