ELFN1 and colorectal carcinoma: For instance, the alteration of GCN5-SND1 cellular location may existed and also correlated with the ELFN1-AS1 levels; histone acetylation may be balanced by HAT and HDAC [66], in parallel to GCN5-SND1; Furthermore, the relationship between ELFN1-AS1 and histological type, stage, and RAS/RAF-MSI of CRC, as well as whether ELFN1-AS1 promote long-range chromatin looping as CCAT1-L in the activation of MYC [67], will be investigated in future studies.