If suggestive findings are identified at the EMG/ ENG and/or musculoskeletal MR, the algorithm provides for the autoimmune panel, including the extended Myositis panel (anti-Mi2/alpha and beta, anti-DNA, Ku, SRP, PL7, PL-12, EJ, OJ, Jo 1, PM-Scl100 and PM-Sc75, Ro-52, NXP2, TIF 1g, SAE1 and MDA5), anti-SRP and anti-HMGCR Ab. This evidence concerns the gene HMGCR and myositis disease.