A significant strong correlation was found between HCMV presence (IE1 gene) and Myc/EZH2 expression in unmethylated GBM biopsies (r = 0.690, p-value = 0.001; r = 0.589, p-value = 0.006; respectively) (Fig. 5d). Here, EZH2 is linked to glioblastoma.