To further decipher the role of HCMV and EZH2-Myc pathway in vivo, we analyzed 37 GBM biopsies (MGMT promoter methylated n = 17 and MGMT promoter unmethylated n = 20) for the presence of HCMV as well as EZH2 and Myc expression. Here, EZH2 is linked to glioblastoma.