Viral lncRNA4.9 and cellular lncRNA HOTAIR transcripts were detected in the EZH2 immunoprecipitated samples corresponding to CEGBCs derived from all HCMV-GBM strains, mostly from MGMT promoter unmethylated HCMV-GBM strains, using RNA CLIP assay (p-value (UI HAs:GBM) = 0.03; p-value (UI HAs: GBM-M) = 0.07; p-value (UI HAs: GBM-UM) = 0.04) (Fig. 7f). The gene discussed is MGMT; the disease is glioblastoma.