In a study undertaken by Kim, Kim27, relative expression of THBS1 and F2 were slightly higher in bladder cancer than in the normal bladder tissue but the difference was not statistically significant (GSE13507; Fig. 7 upper middle & upper right; p > 0.05), suggesting that RPL8, THBS1 and F2 genes potentially play a vital role in bladder cancer progression and metastasis. The gene discussed is RPL8; the disease is urinary bladder cancer.