Through the RPL8-HSPA1A/HSPA4 link, a considerable number of pathways were identified that include bladder cancer, malaria, p53 signaling, ECM-receptor interaction and TGF-beta signaling pathways that in turn, indicate to the molecular pathways associated with NDV persistent infection in TCCSUP bladder cancer cells. The gene discussed is TP53; the disease is urinary bladder cancer.