Through the RPL8-HSPA1A/HSPA4 link, a considerable number of pathways were identified that include bladder cancer, malaria, p53 signaling, ECM-receptor interaction and TGF-beta signaling pathways that in turn, indicate to the molecular pathways associated with NDV persistent infection in TCCSUP bladder cancer cells. This evidence concerns the gene HSPA1A and urinary bladder cancer.