NR3C1 and Anxiety: Among these empirically significant enriched biological processes pathways, the glucocorticoid receptor signaling pathway (GO:0042921; S6A, S6B, S8A and S8B Tables) has been shown to be associated with common behavioral and/or somatic complex disorders, such as anxiety, chronic pain and fatigue syndromes, and to contribute to the development of neuropathic pain [41, 42].