Hemophilia A (HA) is a bleeding disorder caused by a partial or total deficiency in the coagulation factor VIII (FVIII), which results in prolonged oozing after injuries, tooth extractions, or surgery, as well as delayed or recurrent bleeding prior to complete wound healing.[1,2] Based on the coagulation FVIII activity (FVIII:C), HA is classified into 3 phenotypes: severe (FVIII:C < 1%), moderate (1%–5%), and mild (5%–40%).[3]. The gene discussed is F8; the disease is hemorrhagic disease.