ALOX5 and colorectal carcinoma: To investigate the possible mechanism underlying the effect of ALOX5, a total of 1,895 genes co-expressed with ALOX5 that were identified by the cBioPortal website using CRC data from the TCGA database, were applied for Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis and Gene Ontology (GO) functional annotation analysis online on the Metascape website.