CASP4 and rectal cancer: In the present study we demonstrated that 4 CASP4 SNPs (rs571407, rs612987, rs623114, and rs543923) were associated with a longer OS time, and the haplotypes, CCGC (H2) and TCGC (H3), were associated with a reduced risk of mortality compared to the haplotype, CTAT (H1), in patients with rectal cancer receiving postoperative CRT.