Although DAP12 CAR-YT cells have similar cytotoxicity to CD3ζ CAR-YT cells at an E:T of 10:1, DAP12 CAR-YT cells exhibit stronger anti-tumor ability at lower ratios (1:2.5 and 1:5)128, demonstrating the slight advantage of DAP12 with regard to NK cell stimulation. The gene discussed is TYROBP; the disease is neoplasm.