NLRP3 and acute respiratory distress syndrome: The combined analysis allows the use of miRNAs that are highly correlated with the malignant development of COVID‐19, including miR‐3168 and miR‐1228‐5p, as indicators for the diagnosis and prediction of COVID‐19 development.[108] Last, the expression levels of EV‐miRNA that target NLRP3 inflammasome, including EV‐miR‐466g and EV‐miR‐466m‐5p, are significantly increased in bronchoalveolar lavage fluid (BALF) to exacerbate the inflammation in mouse ARDS model, suggesting their use as potential predictors for the clinical diagnosis of ARDS development.[109]