In an analysis of TB disease in the first 5 years restricted to early TST converters, we found 30 associated genes, where the most significant included PARP1 (P = 9.84 × 10−5), WDR4 (P = 5.34 × 10–4), and KLRD1 (P = .002) (Figure 3A; Supplementary Table 4). Here, KLRD1 is linked to tuberculosis.