SMAD3 and concussion: The mTBI and control groups showed a comparative difference in expression of the miR target gene network core protein in the homology of cell division cycle 5-like (CDC5L), cell cycle divided protein 42 (CDC42), E1A binding protein (EP300), SMAD3, signal transducer and activator of transcription 3 (STAT3), and mitogen-activated protein kinase (MAPK) (Figure 6A).